Modeling the Functional Impact of Genetic Variants Associated with Doxorubicin-Induced Cardiotoxicity in Genome-edited Isogenic Human Cells
Modeling the Functional Impact of Genetic Variants Associated with Doxorubicin-Induced Cardiotoxicity in Genome-edited Isogenic Human Cells
批准号:
329881
负责人:
Brunham Liam R
金额:
$7.29万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2015
资助国家:
加拿大
项目状态:
已结题
起止时间:
2015-03-01 至 2016-03-01
中文摘要
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英文摘要
Forty percent of Canadians will develop cancer in their lifetime. Doxorubicin is a one of the most commonly used and effective drugs to treat cancer, but it can cause heart damage in up to one-quarter of patients who receive it. We currently lack ways to
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