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AhR-dependent alterations in the intestinal permeability of C57BL/6 mice following repeated TCDD exposure

AhR-dependent alterations in the intestinal permeability of C57BL/6 mice following repeated TCDD exposure
反复接触 TCDD 后 C57BL/6 小鼠肠道通透性发生 AhR 依赖性变化
批准号：
327844
负责人：
Fader Kelly A
金额：
$7.65万
依托单位：
Michigan State University (E. Lansing)
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2014
资助国家：
加拿大
项目状态：
已结题
起止时间：
2014-10-01 至 2017-10-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=327844&lang=en
关键词：
Aryl Hydrocarbon Receptor (Ahr) Bioinformatics Digestive System Dioxin Metabolic Disorders Non-Alcoholic Fatty Liver Disease (Nafld) Rna-Sequencing Sex-Specificity Toxicology Ussing Chambers

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Approximately 1 in 5 Canadian adults suffer from obesity, elevated blood lipids, high blood pressure and high blood sugar, commonly referred to as Metabolic Syndrome (MetS). In the liver, MetS is first observed as fat accumulation which can develop into n
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