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Characterizing the Role of the Endosomal/ Lysosomal system in beta-Amyloid Production and Secretion in Alzheimer's disease

Characterizing the Role of the Endosomal/ Lysosomal system in beta-Amyloid Production and Secretion in Alzheimer's disease
表征内体/溶酶体系统在阿尔茨海默病中β-淀粉样蛋白产生和分泌中的作用
批准号：
333011
负责人：
Pasternak Stephen H
金额：
$7.29万
依托单位：
University of Western Ontario
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2015
资助国家：
加拿大
项目状态：
已结题
起止时间：
2015-05-01 至 2016-05-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=333011&lang=en
关键词：
Alzheimer'S Disease Cell Biology Confocal Microscopy Endocytosis Fluorescent Protein Tags Live Cell Imaging Macropinocytosis Total Intermal Reflection Microscopy

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中文摘要
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英文摘要
Alzheimer's Disease is the most common neurodegenerative disease in adults. Currently there are more than 750,000 Canadians with Alzheimer's disease, and this number will to rise to over 1 million. Alzheimer's disease is characterized by a buildup of be
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Understanding lysosomal secretion in neurons: a novel mechanism responsible for beta-amyloid release.
Characterizing the role of the endosomal/ lysosomal system in Alzheimer's Disease
  • 批准号：
    200704
  • 项目类别：
    Operating Grants
  • 资助金额：
    $43.87万
  • 财政年份：
    2010
  • 负责人：
    Pasternak Stephen H
  • 依托单位：
    University of Western Ontario
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