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Activation of a cytosolic unfolded protein response to clear aggregating alpha-synuclein

Activation of a cytosolic unfolded protein response to clear aggregating alpha-synuclein
激活胞质未折叠蛋白对透明聚集 α-突触核蛋白的反应
批准号:
390178
负责人:
Girardin Stephen E
金额:
$37.47万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2018
资助国家:
加拿大
项目状态:
已结题
起止时间:
2018-09-01 至 2021-09-01

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中文摘要
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英文摘要
In Parkinson's Disease, a protein called alpha-synuclein forms aggregates that are toxic are result in the death of brain cells. We have discovered a new way by which cells control the folding of proteins, to avoid formation of toxic aggregates. We will e
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Induction of intestinal revSCs by a bacterial metabolite
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    488049
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    Operating Grants
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    $74.96万
  • 财政年份:
    2023
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Mitochondrial protein import stress (MPIS) pathways
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    477303
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    2022
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The impact of early-life enteric infection on the development of Crohn's disease
  • 批准号:
    420463
  • 项目类别:
    Operating Grants
  • 资助金额:
    $58.24万
  • 财政年份:
    2020
  • 负责人:
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  • 依托单位:
Canada Research Chairs - Tier 1
  • 批准号:
    441793
  • 项目类别:
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  • 财政年份:
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  • 负责人:
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海外基金