Identification and mitigation of oxidized phospholipids as a novel mediator of neurodegeneration in the central nervous system.

氧化磷脂作为中枢神经系统神经退行性变的新型介质的鉴定和缓解。

• 批准号: 417675
• 负责人: Dong Yifei
• 金额: $ 9.83万
• 依托单位: University of Calgary
• 依托单位国家: 加拿大
• 项目类别: Fellowship Programs
• 财政年份: 2019
• 资助国家: 加拿大
• 起止时间: 2019-10-01 至 2022-10-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=417675&lang=en
• 关键词: Flow Cyometry; Inflammation; Microglia; Microscopy; Mouse Model; Multiple Sclerosis; Neurodegeneration; Oxidized Phosphatidylcholine; Rna Sequencing; Spinal Cord

Multiple sclerosis (MS) is currently an incurable autoimmune disease of the brain and spinal cord. Patients are afflicted with deteriorating MS for life. We aim to explore new mechanisms that cause nerve destruction during MS to provide better treatments

多发性硬化症（MS）是目前无法治愈的脑和脊髓的自身免疫性疾病。患者终身患有恶化的MS。我们的目标是探索MS期间导致神经破坏的新机制，以提供更好的治疗方法。