Biogenesis of red blood cell membrane modifications by the malaria parasite Plasmodium falciparum

疟原虫恶性疟原虫红细胞膜修饰的生物发生

• 批准号: DP1093518
• 负责人: Prof Dr Alexander Maier
• 金额: $ 23.03万
• 依托单位: The Australian National University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2010
• 资助国家: 澳大利亚
• 起止时间: 2010-01-01 至 2013-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP1093518
• 关键词: Biogenesis; red; blood; cell; membrane

Malaria is not only a major global health problem, but also affects countries neighbouring Australia like Indonesia, reducing the region's stability and prosperity. Environmental changes and increased mobility of people (aid and military personnel) make Australia itself more prone to malaria. The project will translate recent genomic data into functional insights using frontier technology to identify new intervention targets for Plasmodium falciparum infection. Developing novel targets is mandated by humanity, but also to safeguard Australia's region against the social and economic implications of this disease. An Australian developed intervention would increase the global visibility of its science, leading to increased investments.

疟疾不仅是一个重大的全球健康问题，而且还影响到澳大利亚的邻国，如印度尼西亚，削弱了该地区的稳定和繁荣。环境变化和人员（援助人员和军事人员）流动性的增加使澳大利亚本身更容易患疟疾。该项目将利用前沿技术将最近的基因组数据转化为功能见解，以确定恶性疟原虫感染的新干预靶点。开发新的目标是人类的使命，也是为了保护澳大利亚地区免受这种疾病的社会和经济影响。澳大利亚开发的干预措施将提高其科学的全球知名度，从而增加投资。