Functional Genomic Analysis of Exported DNAJ Molecules in the Malaria Parasite Plasmodium falciparum

疟原虫恶性疟原虫输出 DNAJ 分子的功能基因组分析

• 批准号: DP0878953
• 负责人: Prof Dr Alexander Maier
• 金额: $ 34.55万
• 依托单位: The Australian National University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2008
• 资助国家: 澳大利亚
• 起止时间: 2008-01-01 至 2013-01-14
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP0878953
• 关键词: Functional; Genomic; Analysis; Exported; DNAJ

Malaria is not only a global health problem, but also affects countries surrounding Australia like PNG and Indonesia, reducing the region's stability and prosperity. Environmental changes and increased mobility of people (eg. aid and security personnel) make Australia itself more prone to malaria. The project will translate recent genomic data into functional insights using frontier technology to identify new intervention targets for P. falciparum infection. Developing novel targets is mandated by humanity, and also to safeguard Australia's region against the social and economical implication of this disease. An Australian developed intervention would increase the global visibility of its science, leading to increased investments.

疟疾不仅是一个全球性的健康问题，而且还影响到巴布亚新几内亚和印度尼西亚等澳大利亚周边国家，降低了该地区的稳定和繁荣。环境变化和人员流动性增加（例如，援助和安全人员）使澳大利亚本身更容易感染疟疾。该项目将利用前沿技术将最新的基因组数据转化为功能性见解，以确定恶性疟原虫感染的新干预目标。开发新的目标是人类的任务，也是为了保护澳大利亚地区免受这种疾病的社会和经济影响。澳大利亚制定的干预措施将提高其科学在全球的知名度，从而增加投资。