MRE11-RAD50-NBS1: at the crossroads of DNA double-strand break repair and Fanconi anemia
MRE11-RAD50-NBS1: at the crossroads of DNA double-strand break repair and Fanconi anemia
批准号:
188788
负责人:
Masson Jean-Yves
金额:
$59.85万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2009
资助国家:
加拿大
项目状态:
已结题
起止时间:
2009-09-01 至 2014-09-01
中文摘要
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英文摘要
Cancer is a constant treath for humans. All organisms have evolved mechanisms that allow the maintenance of genomic integrity. The consequences of damaged DNA, and especially double-strand breaks, may be disastrous and lead to cancer if left unrepaired. A
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Canada Research Chairs - Tier 1
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批准号:424788
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项目类别:
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资助金额:$101.99万
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财政年份:2019
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负责人:Masson Jean-Yves
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依托单位:
Patient stratification based on DNA repair functionality for cancer precision medicine
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批准号:406820
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项目类别:Operating Grants
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资助金额:$23.52万
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财政年份:2019
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负责人:Masson Jean-Yves
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依托单位:
Decoding the DNA double-strand break repair pathways: from mechanistic insights to human genome instability diseases
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批准号:369216
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项目类别:Operating Grants
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资助金额:$245.17万
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财政年份:2017
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负责人:Masson Jean-Yves
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依托单位:
Roles of the tumor suppressor PALB2 at the crossroads of DNA double-strand break repair and synthetic lethal strategies
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批准号:355281
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项目类别:Operating Grants
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资助金额:$70.5万
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财政年份:2016
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负责人:Masson Jean-Yves
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依托单位:
Mechanisms and regulation of DNA end resection in mammalian cells
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批准号:343190
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项目类别:Operating Grants
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资助金额:$59.59万
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财政年份:2016
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负责人:Masson Jean-Yves
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依托单位:
Interplay between homologous recombination and anti-recombination activities at broken DNA replication forks and genomic instability
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批准号:277932
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项目类别:Operating Grants
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资助金额:$37.47万
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财政年份:2013
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负责人:Masson Jean-Yves
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依托单位:
2nd Canadian Symposium on Telomeres and Genome Integrity
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批准号:298901
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项目类别:Miscellaneous Programs
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资助金额:$1.82万
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财政年份:2013
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负责人:Masson Jean-Yves
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依托单位:
Functions of the tumor suppressor PALB2 in DNA double-strand break repair and tumorigenesis
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批准号:210642
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项目类别:Operating Grants
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资助金额:$54.08万
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财政年份:2010
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负责人:Masson Jean-Yves
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依托单位:
海外基金