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MRE11-RAD50-NBS1: at the crossroads of DNA double-strand break repair and Fanconi anemia

MRE11-RAD50-NBS1: at the crossroads of DNA double-strand break repair and Fanconi anemia
MRE11-RAD50-NBS1:处于DNA双链断裂修复和范可尼贫血的十字路口
批准号:
188788
负责人:
Masson Jean-Yves
金额:
$59.85万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2009
资助国家:
加拿大
项目状态:
已结题
起止时间:
2009-09-01 至 2014-09-01

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英文摘要
Cancer is a constant treath for humans. All organisms have evolved mechanisms that allow the maintenance of genomic integrity. The consequences of damaged DNA, and especially double-strand breaks, may be disastrous and lead to cancer if left unrepaired. A
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Canada Research Chairs - Tier 1
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    424788
  • 项目类别:
  • 资助金额:
    $101.99万
  • 财政年份:
    2019
  • 负责人:
    Masson Jean-Yves
  • 依托单位:
Patient stratification based on DNA repair functionality for cancer precision medicine
  • 批准号:
    406820
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    Operating Grants
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    $23.52万
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    2019
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    Masson Jean-Yves
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Decoding the DNA double-strand break repair pathways: from mechanistic insights to human genome instability diseases
  • 批准号:
    369216
  • 项目类别:
    Operating Grants
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    $245.17万
  • 财政年份:
    2017
  • 负责人:
    Masson Jean-Yves
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Roles of the tumor suppressor PALB2 at the crossroads of DNA double-strand break repair and synthetic lethal strategies
  • 批准号:
    355281
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    Operating Grants
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    $70.5万
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海外基金