Duke PRIME Cancer Research Program

杜克大学 PRIME 癌症研究计划

• 批准号: 10707608
• 负责人: GERARD C BLOBE
• 金额: $ 19.68万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-19 至 2028-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10707608
• 关键词: Academy; Address; Admission activity; Adolescence; Advanced Malignant Neoplasm; Area; Basic Cancer Research; Biomedical Research; Cancer Biology; Cancer Control; Cancer Death Rates; Cancer Research Project; Cancer Science; Cancer Survivor; Career Choice; Caring; Cause of Death; Cessation of life; Childhood; Clinical; Critical Thinking; Death Rate; Dedications; Detection; Development; Discipline; Education; Educational Curriculum; Evaluation; Exposure to; Face; Funding; Future; Goals; Health; Image; Immunooncology; Incidence; Individual; Institution; Internet; Knowledge; Laboratory Research; Link; Malignant Neoplasms; Medical; Medical Students; Medicine; Mentors; Mentorship; Methodology; Modality; Modeling; Morbidity - disease rate; Occupations; Outcome; Pathway interactions; Persons; Physicians' Offices; Positioning Attribute; Postbaccalaureate; Prevalence; Prevention; Professional Competence; Program Sustainability; Radiation Oncology; Research; Research Personnel; Research Training; Resources; Risk; Role; STEM field; Science; Scientist; Structure; Students; Talents; Technical Expertise; Techniques; Therapeutic; Training; Training and Infrastructure; United States; Universities; anticancer research; cancer care; cancer diagnosis; cancer prevention; cancer risk; cancer therapy; cancer type; career; career development; cohort; didactic education; education research; evidence base; experience; falls; graduate school; improved; innovation; interest; laboratory experience; medical schools; meetings; model development; mortality; network models; neuro-oncology; next generation; outreach; peer; peer coaching; peer networks; precision oncology; premature; programs; recruit; skills; success; summer research; tool; undergraduate student; virtual; virtual platform

ABSTRACT The U.S. is facing a biomedical workforce crisis, starting with attrition from STEM majors in undergraduate training. The result is a lack of innovative solutions to advance health outcomes. Cancer remains a significant cause of morbidity and mortality. The prevalence of cancer diagnoses and survivors in the U.S. was more than 19 million in 2020, with 9.9 million cancer-related deaths worldwide. Duke University is uniquely positioned to address this critical problem by building a robust pipeline of future academic cancer researchers. The Duke Cancer Institute (DCI) is nationally recognized for its research programs in the areas of cancer biology; cancer prevention and control; cancer risk detection and interception; immune- oncology; neuro-oncology; precision cancer medicine and investigational therapeutics; and radiation oncology and imaging. Our recently established Office of Physician Scientist Development (OPSD) offers a sustainable structure for mentorship, professional development, and research funding. By leveraging these institutional structures, we are well positioned to support the development, implementation, and evaluation of a program that links resources across the training spectrum to introduce undergraduate students to varied cancer research career opportunities. To address the cancer research workforce gap, we propose the Duke Preparing Research scholars In bioMEdical sciences (PRIME): Cancer Research Program, which will recruit cohorts of undergraduate students and provide them with research skills-building and mentored research experiences in cancer research. We will provide evidence-based professional development activities and sustained engagement through virtual platforms and the opportunity for program alumni to return in peer-to-peer mentor roles. The Duke PRIME: Cancer Research Program will achieve our long-term goal, addressing barriers that limit the recruitment and retention of a cancer research workforce through early exposure to intensive research experiences, an innovative didactics curriculum, and peer networking. The program focuses on 1) providing a mentored summer research intensive experience for undergraduates; 2) providing a parallel OPSD PRIME Academy enrichment curriculum to enhance understanding of FDQFHU research concepts and career paths in research; and 3) developing a peer networking model with sustained engagement throughout the academic year. Successful implementation of the proposed program will lead to a scalable model for development of a robust pipeline for a diverse biomedical research workforce across disciplines.

摘要 美国正面临着生物医学劳动力危机，首先是来自STEM专业的 本科生培训。其结果是缺乏创新的解决方案来改善健康结果。癌 仍然是发病率和死亡率的一个重要原因。年癌症诊断和幸存者的患病率 2020年，美国的癌症死亡人数超过1900万，全球与癌症相关的死亡人数为990万。杜克大学 通过建立强大的未来学术渠道来解决这一关键问题 癌症研究人员。杜克癌症研究所(DCI)因其在 癌症生物学领域；癌症预防和控制；癌症风险检测和拦截；免疫- 肿瘤学；神经肿瘤学；精确癌症医学和研究治疗学；以及放射肿瘤学 和成像。我们最近成立的医生科学家发展办公室(OPSD)提供了一个可持续的 指导、专业发展和研究资金的结构。通过利用这些机构 结构，我们能够很好地支持计划的开发、实施和评估 这将培训范围内的资源联系起来，向本科生介绍各种癌症 研究职业机会。为了解决癌症研究人员的缺口，我们建议杜克大学 培养生物医学研究学者(PRIME)：癌症研究计划， 将招收一批本科生，并为他们提供研究技能建设和 癌症研究方面的指导研究经验。我们将提供循证专业的 通过虚拟平台和计划机会开展开发活动和持续参与 校友将以对等导师的角色回归。Duke Prime：癌症研究计划将实现 我们的长期目标，解决限制招聘和留住癌症研究队伍的障碍 通过早期接触密集的研究经验，创新的教学论课程，以及同行 网络。该计划的重点是1)为以下人员提供有指导的夏季研究强化体验 本科生；2)提供并行的OPSD Prime Academy丰富课程，以增强 了解FDQFHU的研究概念和研究中的职业道路；3)发展同伴网络 在整个学年中持续投入的模特。成功实施 提议的计划将导致一个可扩展的模型，用于开发适用于各种 跨学科的生物医学研究队伍。