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Antiestrogen-HDACi hybrid molecules for breast cancer treatment.

Antiestrogen-HDACi hybrid molecules for breast cancer treatment.
用于乳腺癌治疗的抗雌激素-HDACi 杂合分子。
批准号:
260641
负责人:
Mader Sylvie N
金额:
$7.29万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2012
资助国家:
加拿大
项目状态:
已结题
起止时间:
2012-03-01 至 2013-03-01

项目摘要

项目成果

Mader Sylvie N的其他基金

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中文摘要
翻译
乳腺癌是西方世界女性最常见的癌症。由于雌激素可刺激三分之二的乳腺肿瘤的生长,阻断其作用的化合物(抗雌激素,ae)已在临床上广泛使用
英文摘要
Breast cancer is the most common form of cancer in women in the Western world. As growth of 2/3 of breast tumors can be stimulated by the hormone estrogen, compounds that block its action (antiestrogens, AEs) have been used in the clinic with considerable
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会议论文
Mechanisms of action of antiestrogens in breast cancer: roles of ubiquitin-like modifications in transcriptional inactivation of Estrogen Receptor alpha.
  • 批准号:
    480045
  • 项目类别:
    Operating Grants
  • 资助金额:
    $61.3万
  • 财政年份:
    2023
  • 负责人:
    Mader Sylvie N
  • 依托单位:
Mechanisms of action of antiestrogens in breast cancer: roles of Ubi-like modifications in transcriptional inactivation of Estrogen Receptor alpha.
  • 批准号:
    472352
  • 项目类别:
    Operating Grants
  • 资助金额:
    $7.29万
  • 财政年份:
    2022
  • 负责人:
    Mader Sylvie N
  • 依托单位:
Mechanisms of action of antiestrogens: towards improved treatment of relapse in ER+ breast cancer
  • 批准号:
    372071
  • 项目类别:
    Operating Grants
  • 资助金额:
    $54.34万
  • 财政年份:
    2017
  • 负责人:
    Mader Sylvie N
  • 依托单位:
Mechanisms controlling estrogen receptor alpha expression and activity in breast tumorigenesis
  • 批准号:
    358549
  • 项目类别:
    Operating Grants
  • 资助金额:
    $66.32万
  • 财政年份:
    2016
  • 负责人:
    Mader Sylvie N
  • 依托单位:
海外基金