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Mechanisms controlling estrogen receptor alpha expression and activity in breast tumorigenesis

Mechanisms controlling estrogen receptor alpha expression and activity in breast tumorigenesis
乳腺肿瘤发生中雌激素受体α表达和活性的控制机制
批准号:
358549
负责人:
Mader Sylvie N
金额:
$66.32万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2016
资助国家:
加拿大
项目状态:
已结题
起止时间:
2016-10-01 至 2021-10-01

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中文摘要
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英文摘要
Breast cancer is a prevalent world-wide disease but its manifestations are heterogeneous, necessitating treatment regimen adapted to the main tumor subtypes currently identified. Two thirds of tumors overexpress the estrogen receptor alpha (ER) compared t
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Mechanisms of action of antiestrogens in breast cancer: roles of ubiquitin-like modifications in transcriptional inactivation of Estrogen Receptor alpha.
  • 批准号:
    480045
  • 项目类别:
    Operating Grants
  • 资助金额:
    $61.3万
  • 财政年份:
    2023
  • 负责人:
    Mader Sylvie N
  • 依托单位:
Mechanisms of action of antiestrogens in breast cancer: roles of Ubi-like modifications in transcriptional inactivation of Estrogen Receptor alpha.
  • 批准号:
    472352
  • 项目类别:
    Operating Grants
  • 资助金额:
    $7.29万
  • 财政年份:
    2022
  • 负责人:
    Mader Sylvie N
  • 依托单位:
Mechanisms of action of antiestrogens: towards improved treatment of relapse in ER+ breast cancer
  • 批准号:
    372071
  • 项目类别:
    Operating Grants
  • 资助金额:
    $54.34万
  • 财政年份:
    2017
  • 负责人:
    Mader Sylvie N
  • 依托单位:
Mechanisms of action of full antiestrogens
  • 批准号:
    268027
  • 项目类别:
    Operating Grants
  • 资助金额:
    $50.72万
  • 财政年份:
    2012
  • 负责人:
    Mader Sylvie N
  • 依托单位:
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