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16q hemizygous loss in breast cancer: The central driver for tumor initiation, invasion and progression

16q hemizygous loss in breast cancer: The central driver for tumor initiation, invasion and progression
乳腺癌16q半合子缺失：肿瘤发生、侵袭和进展的核心驱动因素
批准号：
452128
负责人：
Egan Sean E
金额：
$71.33万
依托单位：
Hospital for Sick Children (Toronto)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2021
资助国家：
加拿大
项目状态：
未结题
起止时间：
2021-09-01 至 2026-09-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=452128&lang=en
关键词：
Breast Cancer Genetics Mouse Modeling Theraepeutics Tumor Suppressors

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英文摘要
The most common events in breast cancer involve losses or gains of entire chromosome arms. Indeed, the loss of a specific arm, 16q, is the single most common event, occurring in up to 65% of breast tumors. Despite this, the literature is focused almost e
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Journal of Genetics and Genomics