Addressing tumor heterogeneity through identification of subgroup-specific "shared maintenance genes" - the right target for each cancer

通过识别亚组特异性的“共享维持基因”来解决肿瘤异质性——每种癌症的正确目标

• 批准号: 222470
• 负责人: Egan Sean E
• 金额: --
• 依托单位: Hospital for Sick Children (Toronto)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2010
• 资助国家: 加拿大
• 起止时间: 2010-12-01 至 2013-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=222470&lang=en
• 关键词: Breast Cancer; Medulloblastoma; Metastasis; Oncogene Addiction; P53; Pi3k; Rb; Shared Maintenance Genes; Shh; Wnt

Metastasis is the process by which tumor cells seed secondary tumors elsewhere in the body. While many brain and breast cancers are cured through a combination of surgery and chemotherapy or radiation therapy, metastatic disease is frequently incurable.

转移是肿瘤细胞在身体其他地方种植继发性肿瘤的过程。 虽然许多脑癌和乳腺癌可以通过手术和化疗或放射治疗的结合来治愈，但转移性疾病通常是无法治愈的。