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Therapy-Related Hepatic Mitochondrial Toxicity in HepG2 Cells and in Patients Co-Infected with HIV and Hepatitis C Virus

Therapy-Related Hepatic Mitochondrial Toxicity in HepG2 Cells and in Patients Co-Infected with HIV and Hepatitis C Virus
HepG2 细胞以及同时感染 HIV 和丙型肝炎病毒的患者中与治疗相关的肝线粒体毒性
批准号：
195923
负责人：
Wade Rachel E
金额：
$4.81万
依托单位：
University of British Columbia
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2009
资助国家：
加拿大
项目状态：
已结题
起止时间：
2009-10-01 至 2012-10-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=195923&lang=en
关键词：
Autophagy Cell Culture Co-Infection Hepatitis C Virus Highly Active Antiretroviral Therapy (Haart) Hiv/Aids Liver Mitochondrial Toxicity Mutations Sequencing

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HIV and hepatitis C virus (HCV) share common routes of infection so that individuals are often infected with both. In BC, a third of HIV patients are co-infected with HCV. Half of HIV-infected individuals die of liver disease and of those, over 90% are co
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