Remote Fiber Optic Biosensors: Optically Controlled Ligand Delivery

远程光纤生物传感器：光控配体输送

• 批准号: 8502107
• 负责人: Joseph Andrade
• 金额: $ 22.64万
• 依托单位: University of Utah
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1985
• 资助国家: 美国
• 起止时间: 1985-08-01 至 1989-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=8502107&HistoricalAwards=false
• 关键词: Remote; Fiber; Optic; Biosensors; Optically

This project will study and develop a system to deliver chemicals into the body by controlled lightwave pulses. The optically controlled system will unbind some stored chemical which will diffuse to a second optical fiber which contains monoclonal antibodies immobilized on its surface. The resulting system constitutes a remote, competitive binding immunoassay which can be performed under optical control. This will open up new possibilities in the treatment of patients as well as in industrial process control. Remote optical reagent generation will be a major tool in biological research, allowing precisely controlled ;itin situ;ro delivery of chemicals into microscopic areas.

该项目将研究和开发一个系统，将化学品输送到 通过受控的光波脉冲来治疗身体。 光控 系统将释放一些储存的化学物质，这些化学物质将扩散到第二个 含有固定在其上的单克隆抗体的光纤 面 由此产生的系统构成了一个远程的， 可以在光学控制下进行的结合免疫测定。 这 将为患者的治疗开辟新的可能性， 工业过程控制。 远程光学试剂生成将 是生物学研究中的一个主要工具， 原位;ro将化学品输送到微观区域。