U.S.-Korea Cooperative Research on Protein Interactions withGradient Surfaces

美韩合作研究蛋白质与梯度表面的相互作用

• 批准号: 8719079
• 负责人: Joseph Andrade
• 金额: $ 1.78万
• 依托单位: University of Utah
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1988
• 资助国家: 美国
• 起止时间: 1988-07-15 至 1992-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=8719079&HistoricalAwards=false
• 关键词: U.S.; Korea; Cooperative; Research; Protein

This proposal requests funds to permit Dr. Joseph D. Andrade, Department of Bioengineering, University of Utah, to pursue with Dr. Hai Bang Lee, Polymer Laboratory, Korea Research Institute of Chemical Technology, for a period of 24 months, a program of cooperative research on protein interactions with gradient surfaces. The collaborators will prepare and characterize samples which exhibit a continuous range of surface properties and study the interactions of a set of proteins with these surfaces. The U.S. team will prepare surfaces by a solution process, while the Korean team will use a "dry" vacuum process. Both groups will study surface characterization - the U.S. group studying protein adsorption, the Korean group studying cell adhesion on surfaces before and after protein treatment. Both group will work on data interpretation and hypothesis refinement. Protein adsorption at solid-liquid interfaces is important in many applications and industries, including separations, biotechnology, medical devices, and diagnostic products. The collaborators are highly respected scientists who have long been engaged in polymer research. The present project will allow them to combine their talents in complimentary approaches to a study of the research problem. This project is relevant to the objectives of the U.S.-Korea Cooperative Science Program which seeks to increase the level of cooperation between U.S. and Korean scientists and engineers through the exchange of scientific information, ideas, skills, and techniques and through collaboration on problems of mutual benefit.

该提案要求资金允许约瑟夫·D博士。安德拉德， 犹他州大学生物工程系， Hai Bang Lee博士，韩国聚合物研究所聚合物实验室 化学技术，为期24个月，一个项目 蛋白质与梯度表面相互作用的合作研究。 合作者将准备和表征样品， 连续范围的表面性质，并研究一个 一组蛋白质与这些表面。 美国队将准备 表面的解决方案的过程中，而韩国队将使用"干" 真空工艺。 两个小组都将研究表面特征- 研究蛋白质吸附的美国小组，研究细胞的韩国小组 在蛋白质处理之前和之后的表面上的粘附。 两组 将致力于数据解释和假设完善。 蛋白质在固-液界面的吸附在许多生物技术中是重要的。 应用和工业，包括分离，生物技术， 医疗器械和诊断产品。 合作者高度 长期从事聚合物研究的受人尊敬的科学家。 目前的项目将使他们能够联合收割机， 对研究问题的研究的补充方法。 这 该项目与美国的目标有关-韩国合作社 旨在提高合作水平的科学计划 美国和韩国的科学家和工程师通过交流， 科学信息、思想、技能和技术， 在互惠互利的问题上进行合作。