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AR locus amplification awakens transposable elements to promote metastatic castration-resistant prostate cancer

AR locus amplification awakens transposable elements to promote metastatic castration-resistant prostate cancer
AR位点扩增唤醒转座因子促进转移性去势抵抗性前列腺癌
批准号:
487981
负责人:
Lupien Mathieu
金额:
$63.53万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2023
资助国家:
加拿大
项目状态:
未结题
起止时间:
2023-09-01 至 2028-09-01

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中文摘要
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英文摘要
Even with the advancements in initial treatments for prostate cancer, the disease can still become deadly when it progresses to a stage called metastatic castration-resistant prostate cancer (mCRPC). Five years ago, amplification of the Androgen Receptor
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会议论文
Chromatin context of somatic mutations delineate oncogenic drivers in triple-negative breast cancer
  • 批准号:
    408421
  • 项目类别:
    Operating Grants
  • 资助金额:
    $61.3万
  • 财政年份:
    2019
  • 负责人:
    Lupien Mathieu
  • 依托单位:
Overcoming chemotherapy-resistance in triple-negative breast cancer
  • 批准号:
    381089
  • 项目类别:
    Operating Grants
  • 资助金额:
    $109.28万
  • 财政年份:
    2018
  • 负责人:
    Lupien Mathieu
  • 依托单位:
Delineating therapeutic opportunities in Triple-Negative Breast Cancer
Delineating the role of noncoding mutations in prostate cancer
  • 批准号:
    355590
  • 项目类别:
    Operating Grants
  • 资助金额:
    $69.66万
  • 财政年份:
    2016
  • 负责人:
    Lupien Mathieu
  • 依托单位:
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