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Investigating the role of EZH2 genomic localization in the response to EZH2 inhibition in breast cancer subtypes

Investigating the role of EZH2 genomic localization in the response to EZH2 inhibition in breast cancer subtypes
研究 EZH2 基因组定位在乳腺癌亚型中 EZH2 抑制反应中的作用
批准号:
304833
负责人:
Lupien Mathieu
金额:
$52.38万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2014
资助国家:
加拿大
项目状态:
已结题
起止时间:
2014-03-01 至 2019-03-01

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中文摘要
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英文摘要
Breast cancer is a significant health concern in Canada, with an estimated 23,800 women being diagnosed and 5,100 dying from the disease in 2013. While targeted therapies exist for those breast cancers determined to be expressing hormone receptors or the
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AR locus amplification awakens transposable elements to promote metastatic castration-resistant prostate cancer
  • 批准号:
    487981
  • 项目类别:
    Operating Grants
  • 资助金额:
    $63.53万
  • 财政年份:
    2023
  • 负责人:
    Lupien Mathieu
  • 依托单位:
Chromatin context of somatic mutations delineate oncogenic drivers in triple-negative breast cancer
  • 批准号:
    408421
  • 项目类别:
    Operating Grants
  • 资助金额:
    $61.3万
  • 财政年份:
    2019
  • 负责人:
    Lupien Mathieu
  • 依托单位:
Overcoming chemotherapy-resistance in triple-negative breast cancer
  • 批准号:
    381089
  • 项目类别:
    Operating Grants
  • 资助金额:
    $109.28万
  • 财政年份:
    2018
  • 负责人:
    Lupien Mathieu
  • 依托单位:
Delineating therapeutic opportunities in Triple-Negative Breast Cancer
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