Materials Characterization and Bone Growth Conduction of Hydroxyapatite Linings on Porous Titanium

人工髋关节的植入已经成为标准的骨科治疗；然而，植入物的失败率需要更好地了解所涉及的材料。本研究的主要目的是为了加深对影响骨结合和骨生长传导性能的材料参数的了解，即多孔钛表面薄层HA衬里对骨-种植体界面骨生长的影响。通过改变沉积过程开始时HA粉末的选择、涂层厚度、沉积方法和注入时间来研究这一过程。将进行体内和体外研究。

The implantation of artificial hip joints has become standard orthopedic treatment; however, the failure rate of the implants demands a better understanding of the materials involved. The main objective of this research is to improve the understanding of material parameters which influence bone bonding and bone growth conduction properties that thin linings of HA on porous titanium influences the ingrowth of bone at the bone-implant interface. The process will be studied by varying the choice of HA powders with which the deposition process starts, the coating thickness, the method of deposition, and the time implantation. Both in-vivo and in-vitro studies will be performed.