Materials Characterization and Bone Growth Conduction of Hydroxyapatite Linings on Porous Titanium

多孔钛上羟基磷灰石衬里的材料表征和骨生长传导

• 批准号: 8515031
• 负责人: Paul Ducheyne
• 金额: --
• 依托单位: University of Pennsylvania
• 依托单位国家: 美国
• 项目类别: Continuing grant
• 财政年份: 1986
• 资助国家: 美国
• 起止时间: 1986-04-15 至 1990-01-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=8515031&HistoricalAwards=false
• 关键词: Materials; Characterization; Bone; Growth; Conduction

The implantation of artificial hip joints has become standard orthopedic treatment; however, the failure rate of the implants demands a better understanding of the materials involved. The main objective of this research is to improve the understanding of material parameters which influence bone bonding and bone growth conduction properties that thin linings of HA on porous titanium influences the ingrowth of bone at the bone-implant interface. The process will be studied by varying the choice of HA powders with which the deposition process starts, the coating thickness, the method of deposition, and the time implantation. Both in-vivo and in-vitro studies will be performed.

人工髋关节的植入已经成为标准 矫形治疗;然而，植入物的失败率要求 更好地理解所涉及的材料。 主要目标 提高对材料参数的认识 其影响骨结合和骨生长传导性质， 多孔钛上HA的薄层内衬影响骨长入 在骨-植入物界面。 该过程将通过改变 沉积过程开始时HA粉末的选择， 涂层厚度、沉积方法和注入时间。 将进行体内和体外研究。