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Design, Synthesis and Testing of Proteolytically Stable Analogs of Apelin-13 for Treatment of Cardiovascular Disease

Design, Synthesis and Testing of Proteolytically Stable Analogs of Apelin-13 for Treatment of Cardiovascular Disease
用于治疗心血管疾病的 Apelin-13 蛋白水解稳定类似物的设计、合成和测试
批准号：
305137
负责人：
Vederas John C
金额：
$38.9万
依托单位：
University of Alberta
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2014
资助国家：
加拿大
项目状态：
已结题
起止时间：
2014-03-01 至 2019-03-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=305137&lang=en
关键词：
Cardiovascular Agent Drug Bioavailability Peptide Peptide Protein Interactions Peptidomimetic Protease Resistance Receptor Identification Structure-Activity Relationships

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英文摘要
In 2008, approximately 17 million deaths worldwide were attributed to diseases of the cardiovascular system by the World Health Organization. It is predicted that by 2030, almost 23.6 million people will die from heart disease and stroke. Furthermore, the
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