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Design, Synthesis and Testing of Proteolytically Stable Analogs of Apelin-13 and Apelin-17 for Treatment of Cardiovascular Disease

Design, Synthesis and Testing of Proteolytically Stable Analogs of Apelin-13 and Apelin-17 for Treatment of Cardiovascular Disease
用于治疗心血管疾病的 Apelin-13 和 Apelin-17 蛋白水解稳定类似物的设计、合成和测试
批准号：
400605
负责人：
Vederas John C
金额：
$51.27万
依托单位：
University of Alberta
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2019
资助国家：
加拿大
项目状态：
已结题
起止时间：
2019-03-01 至 2024-03-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=400605&lang=en
关键词：
Cardiovascular Agent Drug Bioavailability Drug Delivery Peptide Peptide Protein Interactions Peptidomimetic Protease Resistance Receptor Ligand Interaction Structure-Activity Relationships

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中文摘要
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英文摘要
Approximately 17.7 million deaths worldwide were attributed to diseases of the cardiovascular system by the World Health Organization. About 80% are due to heart attack or stroke. It is predicted that by 2030, almost 23.6 million people will die from hear
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