Cellular Transport Mechanisms in Elasmobranch Kidney Tubules

软骨鱼类肾小管中的细胞运输机制

• 批准号: 8702159
• 负责人: Peter Friedman
• 金额: $ 5.72万
• 依托单位: Mount Desert Island Biological Laboratory
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1987
• 资助国家: 美国
• 起止时间: 1987-07-15 至 1990-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=8702159&HistoricalAwards=false
• 关键词: Cellular; Transport; Mechanisms; Elasmobranch; Kidney

Sharks and other elasmobranchs accumulate high concentrations of urea in the tissues and blood as osmotic buffers to prevent water loss in sea water. The long-term objective of these studies is the identification of mechanisms responsible for the reabsorption of urea in the kidney of elasmobranch fish. A tentative model has been developed to account for the reabsorption of urea against a large chemical concentration gradient. Further characterization of this system will continue. It is anticipated that these studies will lead to a better understanding of the physiological mechanisms of urea transport and conservation in elasmobranch fish.

鲨鱼和其他板鳃类动物 组织和血液中的尿素浓度作为渗透压 缓冲器，以防止海水中的水分流失。 长期 这些研究的目的是确定机制 负责肾脏中尿素的重吸收， 板鳃鱼 已经开发了一个试验性模型， 说明尿素对一种大的化学物质的重吸收 浓度梯度 该系统的进一步表征 将继续 预计这些研究将导致 更好地了解尿素的生理机制 板鳃类鱼类的运输和保护。