Biochemistry of Luminescence

发光生物化学

• 批准号: 8703463
• 负责人: Osamu Shimomura
• 金额: $ 29万
• 依托单位: Marine Biological Laboratory
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1987
• 资助国家: 美国
• 起止时间: 1987-07-01 至 1990-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=8703463&HistoricalAwards=false
• 关键词: Biochemistry; Luminescence

The goal of this project is to undertand this biochemical mechanism and biological function of bioluminescence, that is, to delineate the mechanism involved in the conversion of chemical energy into light energy and to elucidate the roles of luminescence in the physiology of the organisms. To achieve this goal it is essential to determine the chemical structures of the key substances involved in the bioluminescent reactions that occur in diverse types of organisms. The specific aims of the project in the next three years are: (1) to investigate fungal luminescence, including the determination of the structure of fungal luciferin, using Panellus stipticus, (2) to complete current studies in progress, including structural work on the fluorescent substance F of euphasolids, the chromophores of the photoproteins of the millipede Luminodesmus and the brittle star Ophiopsilla, and the green fluorescent protein of Aequorea.

这个项目的目标是了解这种生物化学 生物发光的机制和生物学功能，即， 描述了转换的机制， 化学能转化为光能，并阐明 发光在生物体生理学中的作用。 实现 为了达到这个目的，必须确定化学结构 参与生物发光反应的关键物质 发生在不同类型的生物体中。 该项目在今后三年的具体目标是： (1)研究真菌发光，包括 真菌毒素结构的测定，使用 Panellus stipticus，（2）完成当前的研究 进展情况，包括荧光 Euphasolids的F物质， 千足虫Luminodesmus和脆 星星蛇蚤和绿色荧光蛋白 水母