Addition of a Multipurpose Luminescence Spectrometer to Enhance the Undergraduate Biochemistry and Chemistry Laboratories

添加多用途发光光谱仪以增强本科生物化学和化学实验室

• 批准号: 9850847
• 负责人: Elizabeth Roberts-Kirchhoff
• 金额: $ 1.68万
• 依托单位: University of Detroit Mercy
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-08-01 至 2000-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9850847&HistoricalAwards=false
• 关键词: Addition; Multipurpose; Luminescence; Spectrometer; Enhance

The acquisition of a versatile luminescence spectrometer that can measure fluorescence, phosphorescence, and chemiluminescence will enhance the laboratories in biochemistry, instrumental analysis and general, organic, and physical chemistry and positively impact the undergraduate research experience. The luminescence instrument will be used for identification, analysis, study of molecular dynamics and conformations of biomolecules in solution including interactions with ligands, and enzyme kinetics. The wide use of fluorescence, phosphorescence, and chemiluminescence in chemical, biological, and biochemical research makes it imperative that our undergraduates appreciate the sensitivity and versatility of these techniques. The luminescence spectrometer will be an integral part of the implementation of the mini-research project approach in the biochemistry laboratory that will allow students to develop problem solving skills with the proper supervision to ensure that they are exposed to a wide variety of research and experimental approaches. Implementation of the mini-project approach in the biochemistry laboratory, as well as the new experiments designed for this laboratory and the other laboratories across the curriculum, will be shared with colleagues within a professional forum. Through the integration of luminescence spectroscopy into many of the undergraduate laboratory courses, the students will obtain a solid understanding of luminescence spectroscopy and its many applications. This will impact the chemistry and biochemistry majors within our department, but also majors from other departments including chemical engineering and biology, who enroll in one or more of our laboratory courses. It will allow us to provide our students, many of whom are under-represented minorities and women, with a strong foundation in chemistry and biochemistry, which is necessary to pursue their goals of an advanced degree or professional employment.

一个多功能的发光光谱仪，可以测量荧光，磷光和化学发光的收购将提高在生物化学，仪器分析和一般，有机和物理化学实验室，并积极影响本科生的研究经验。发光仪器将用于识别、分析、研究溶液中生物分子的分子动力学和构象，包括与配体的相互作用和酶动力学。荧光，磷光和化学发光在化学，生物和生物化学研究中的广泛使用使得我们的本科生必须了解这些技术的灵敏度和多功能性。发光光谱仪将是生物化学实验室实施小型研究项目方法的一个组成部分，这将使学生在适当的监督下培养解决问题的技能，以确保他们接触到各种各样的研究和实验方法。在生物化学实验室实施小型项目方法，以及为该实验室和课程中的其他实验室设计的新实验，将在专业论坛中与同事分享。通过将发光光谱学整合到许多本科实验室课程中，学生将对发光光谱学及其许多应用有深入的了解。这将影响我们部门内的化学和生物化学专业，但也从其他部门，包括化学工程和生物学，谁在我们的一个或多个实验室课程注册的专业。这将使我们能够为我们的学生，其中许多人是代表性不足的少数民族和妇女，在化学和生物化学，这是必要的追求他们的目标的高级学位或专业就业的坚实基础。