Addition of a Multipurpose Luminescence Spectrometer to Enhance the Undergraduate Biochemistry and Chemistry Laboratories

获得一台可以测量荧光、磷光和化学发光的多功能发光光谱仪，将提高生物化学、仪器分析和普通、有机化学和物理化学的实验室水平，并对本科生的研究经验产生积极影响。该发光仪将用于鉴定、分析、研究溶液中生物分子的分子动力学和构象，包括与配体的相互作用和酶动力学。荧光、磷光和化学发光在化学、生物和生化研究中的广泛应用使得我们的本科生必须认识到这些技术的敏感性和多功能性。发光光谱仪将是在生物化学实验室实施微型研究项目方法的一个组成部分，该方法将使学生在适当的监督下发展解决问题的技能，以确保他们接触到各种研究和实验方法。在生物化学实验室实施微型项目方法，以及为该实验室和整个课程中的其他实验室设计的新实验，将在一个专业论坛上与同事们分享。通过将发光光谱学整合到许多本科实验课程中，学生将对发光光谱学及其许多应用有一个坚实的了解。这将影响到我们系的化学和生物化学专业，也会影响到其他系的专业，包括化学工程和生物，他们报名参加我们的一门或多门实验室课程。它将使我们的学生，其中许多是代表不足的少数族裔和女性，在化学和生物化学方面有坚实的基础，这是追求他们的高级学位或专业就业目标所必需的。

The acquisition of a versatile luminescence spectrometer that can measure fluorescence, phosphorescence, and chemiluminescence will enhance the laboratories in biochemistry, instrumental analysis and general, organic, and physical chemistry and positively impact the undergraduate research experience. The luminescence instrument will be used for identification, analysis, study of molecular dynamics and conformations of biomolecules in solution including interactions with ligands, and enzyme kinetics. The wide use of fluorescence, phosphorescence, and chemiluminescence in chemical, biological, and biochemical research makes it imperative that our undergraduates appreciate the sensitivity and versatility of these techniques. The luminescence spectrometer will be an integral part of the implementation of the mini-research project approach in the biochemistry laboratory that will allow students to develop problem solving skills with the proper supervision to ensure that they are exposed to a wide variety of research and experimental approaches. Implementation of the mini-project approach in the biochemistry laboratory, as well as the new experiments designed for this laboratory and the other laboratories across the curriculum, will be shared with colleagues within a professional forum. Through the integration of luminescence spectroscopy into many of the undergraduate laboratory courses, the students will obtain a solid understanding of luminescence spectroscopy and its many applications. This will impact the chemistry and biochemistry majors within our department, but also majors from other departments including chemical engineering and biology, who enroll in one or more of our laboratory courses. It will allow us to provide our students, many of whom are under-represented minorities and women, with a strong foundation in chemistry and biochemistry, which is necessary to pursue their goals of an advanced degree or professional employment.