Addition of a Multipurpose Luminescence Spectrometer to Enhance the Undergraduate Biochemistry and Chemistry Laboratories
Addition of a Multipurpose Luminescence Spectrometer to Enhance the Undergraduate Biochemistry and Chemistry Laboratories
批准号:
9850847
负责人:
Elizabeth Roberts-Kirchhoff
金额:
$1.68万
依托单位国家:
美国
项目类别:
Standard Grant
财政年份:
1998
资助国家:
美国
项目状态:
已结题
起止时间:
1998-08-01 至 2000-07-31
中文摘要
获得一台可以测量荧光,磷光和化学发光的多功能发光光谱仪将加强生物化学,仪器分析和一般,有机和物理化学的实验室,并对本科生的研究经历产生积极影响。该发光仪器将用于鉴定、分析、研究溶液中生物分子的分子动力学和构象,包括与配体的相互作用和酶动力学。荧光、磷光和化学发光在化学、生物学和生物化学研究中的广泛应用,使得我们的本科生必须了解这些技术的敏感性和多功能性。发光光谱仪将是生物化学实验室小型研究项目方法实施的一个组成部分,它将允许学生在适当的监督下发展解决问题的技能,以确保他们接触到各种各样的研究和实验方法。在生物化学实验室实施的小项目方法,以及为本实验室和课程中其他实验室设计的新实验,将在专业论坛上与同事分享。通过将发光光谱学整合到许多本科实验课程中,学生将对发光光谱学及其许多应用有一个扎实的了解。这将影响到我们系的化学和生物化学专业的学生,也会影响到其他系的学生,包括化学工程和生物,他们参加了我们的一门或多门实验课程。这将使我们能够为我们的学生提供化学和生物化学的坚实基础,其中许多学生是少数民族和女性,这对于追求更高学位或专业就业的目标是必要的。
英文摘要
The acquisition of a versatile luminescence spectrometer that can measure fluorescence, phosphorescence, and chemiluminescence will enhance the laboratories in biochemistry, instrumental analysis and general, organic, and physical chemistry and positively impact the undergraduate research experience. The luminescence instrument will be used for identification, analysis, study of molecular dynamics and conformations of biomolecules in solution including interactions with ligands, and enzyme kinetics. The wide use of fluorescence, phosphorescence, and chemiluminescence in chemical, biological, and biochemical research makes it imperative that our undergraduates appreciate the sensitivity and versatility of these techniques. The luminescence spectrometer will be an integral part of the implementation of the mini-research project approach in the biochemistry laboratory that will allow students to develop problem solving skills with the proper supervision to ensure that they are exposed to a wide variety of research and experimental approaches. Implementation of the mini-project approach in the biochemistry laboratory, as well as the new experiments designed for this laboratory and the other laboratories across the curriculum, will be shared with colleagues within a professional forum. Through the integration of luminescence spectroscopy into many of the undergraduate laboratory courses, the students will obtain a solid understanding of luminescence spectroscopy and its many applications. This will impact the chemistry and biochemistry majors within our department, but also majors from other departments including chemical engineering and biology, who enroll in one or more of our laboratory courses. It will allow us to provide our students, many of whom are under-represented minorities and women, with a strong foundation in chemistry and biochemistry, which is necessary to pursue their goals of an advanced degree or professional employment.
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