Photoperiodic Regulation of Seasonal Reproduction

季节性繁殖的光周期调节

• 批准号: 8710099
• 负责人: Fred Karsch
• 金额: $ 30.99万
• 依托单位: Regents of the University of Michigan - Ann Arbor
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1987
• 资助国家: 美国
• 起止时间: 1987-12-01 至 1992-11-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=8710099&HistoricalAwards=false
• 关键词: Photoperiodic; Regulation; Seasonal; Reproduction

Virtually all animals undergo marked changes in body structure, function and behavior which enable them to adapt to, and survive, the hardships of a seasonally changing natural environment. The overall goal of the program is to understand the regulation of seasonal reproduction in an animal of world-wide importance, the domestic sheep. It has become clear through recent research that the process of seasonal reproduction in sheep is generated spontaneously by a self-sustained endogenous rhythm of neuroendocrine activity. Changes in day length provide time cues which permit appropriate phasing of this endogenous rhythm with cyclic changes in the environment. The specific goal of the research program is to define those portions of the annual cycle of day length which provide the temporal information leading to an appropriately timed breeding season, and to clarify the mechanisms by which this information is conveyed. The outcome of the research should lead to new insights into a fundamental problem of enormous biological significance and practical importance: the regulation of fertility. The results will also be more broadly applicable to a wide variety of physiological, metabolic and behavioral rhythms which form an integral part of the adaptive mechanisms in many animals. An understanding of these processes should have profound implications to the production of food and human nutrition as well as the reproductive biology of wild or endangered species that are seasonal breeders.

几乎所有的动物都会经历身体结构的显著变化， 功能和行为，使他们能够适应，并生存， 季节性变化的自然环境带来的艰辛 的 该计划的总体目标是了解监管 季节性繁殖的动物在世界范围内的重要性， 家养羊 最近的研究表明， 绵羊的季节性繁殖过程 自发地通过自我维持的内源性节律， 神经内分泌活动 白天长度的变化提供了时间线索 这允许适当地调整这种内源性节律， 环境的周期性变化。 的具体目标 研究计划是确定这些部分的年度周期， 提供时间信息， 一个适当时机的繁殖季节，并澄清 传递这些信息的机制。 的结果 这项研究应该会对一个基本的 具有重大生物学意义和实际意义的问题 重要性：生育率的调节。 结果也将 可以更广泛地应用于各种各样的生理， 代谢和行为节奏，形成一个组成部分， 许多动物的适应机制。 了解 这些进程应该对 粮食和人类营养的生产以及 野生或濒危物种的生殖生物学， 季节性繁殖者