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Exploring GPCR functional selectivity for anti-inflammatory drugs

Exploring GPCR functional selectivity for anti-inflammatory drugs
探索抗炎药物的 GPCR 功能选择性
批准号：
306304
负责人：
Bouvier Michel
金额：
$8.45万
依托单位：
Universit de Montral
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2014
资助国家：
加拿大
项目状态：
已结题
起止时间：
2014-03-01 至 2016-03-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=306304&lang=en
关键词：
Bioluminescence Resonance Energy Transfer Biosensors Functional Selectivity G Protein-Coupled Receptors Inflamatory Chemokines Inflammatory Diseases Protease-Activated Receptor

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英文摘要
The present proposal aims at characterizing the mechanism of action of novel anti-inflammatory drug candidates. These drug candidates target as their site of action a member of a large family of membrane proteins known as G protein-coupled receptors (GPCR
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