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Assembly, trafficking and functional selectivity of G protein-coupled receptors; from molecular mechanisms to therapeutic discovery

Assembly, trafficking and functional selectivity of G protein-coupled receptors; from molecular mechanisms to therapeutic discovery
G蛋白偶联受体的组装、运输和功能选择性；
批准号：
333658
负责人：
Bouvier Michel
金额：
$298.04万
依托单位：
Universit de Montral
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2015
资助国家：
加拿大
项目状态：
已结题
起止时间：
2015-09-01 至 2022-09-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=333658&lang=en
关键词：
Biosensors Cancer Cell Signalling Drug Discovery G Protein-Coupled Receptor Metabolic And Cardiovascular Diseases Protein-Protein Interaction Receptor Regulation Receptor Trafficking Resonance Energy Transfer (Bret-Fret)

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中文摘要
翻译
许多激素和递质通过调节细胞表面受体的活性来产生生物学效应。其中，G蛋白偶联受体（GPCR）代表参与信息传输的最大蛋白质家族
英文摘要
Many hormones and transmitters have their biological effects by modulating the activity of receptors located at the surface of cells. Among these, G protein-coupled receptors (GPCR) represent the largest family of protein involved in transferring informat
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国内基金
海外基金
中国北方人群肺癌患者Cancer/Testis抗原表达谱绘制表位鉴定及功能性抗原特异性CTL制备研究
  • 批准号：
    81673007
  • 项目类别：
    面上项目
  • 资助金额：
    54.0万元
  • 批准年份：
    2016
  • 负责人：
    金时
  • 依托单位：
    哈尔滨医科大学