课题基金 / 基金详情

Conformational Transitions in Polypeptides

Conformational Transitions in Polypeptides
多肽的构象转变
批准号:
8722238
负责人:
Wayne Mattice
金额:
$20.0万
依托单位:
依托单位国家:
美国
项目类别:
Standard Grant
财政年份:
1988
资助国家:
美国
项目状态:
已结题
起止时间:
1988-07-01 至 1991-12-31

项目摘要

项目成果

Wayne Mattice的其他基金

相似基金

相关文献

中文摘要
翻译
理论和实验相结合的方法将被用来理解多肽链中如何形成β-折叠。这项研究的理论部分将继续马蒂斯博士最近提出的贝塔薄片到线圈转变理论的演变。还将开发荧光方法来研究板材到盘管的转变。尽管知道α螺旋和β折叠的结构已经有一段时间了,但目前对螺旋形成的了解远远超过了对β折叠形成的了解。马蒂斯博士的理论工作代表着在理解蛋白质变性和折叠的基本物理化学方面取得了重大进展。
英文摘要
A combination of theoretical and experimental methods will be used to understand how beta sheets are formed in polypeptide chains. The theoretical portion of the research will continue the evolution of Dr. Mattice's recently introduced theory of the beta sheet to coil transition. Fluorescence methods will also be developed for study of the sheet to coil transition. Although the structures of alpha helix and beta sheets have been known for some time, the current understanding of helix formation far surpasses the knowledge of the formation of beta sheets. The theoretical work done by Dr. Mattice represents a significant advance in understanding the basic physical chemistry of protein denaturation and folding.***
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Configuration and Dynamics in Large Polymer Systems
  • 批准号:
    0098321
  • 项目类别:
    Continuing Grant
  • 资助金额:
    $46.0万
  • 财政年份:
    2001
  • 负责人:
    Wayne Mattice
  • 依托单位:
Configuration and Dynamics in Large Polymeric Systems
  • 批准号:
    9523278
  • 项目类别:
    Continuing Grant
  • 资助金额:
    $45.0万
  • 财政年份:
    1996
  • 负责人:
    Wayne Mattice
  • 依托单位:
U.S.-Switzerland-Germany Cooperation in the Semi-Atomistic Simulation of Macromolecules
  • 批准号:
    9421585
  • 项目类别:
    Standard Grant
  • 资助金额:
    $2.46万
  • 财政年份:
    1995
  • 负责人:
    Wayne Mattice
  • 依托单位:
U.S.-Turkey Cooperative Research on Dynamics in Polymeric Systems
  • 批准号:
    9312285
  • 项目类别:
    Continuing Grant
  • 资助金额:
    $3.06万
  • 财政年份:
    1993
  • 负责人:
    Wayne Mattice
  • 依托单位:
海外基金