Photoinduced Palladium Catalysis for Next Generation C-H Bond Activation

光诱导钯催化下一代 C-H 键活化

• 批准号: DP230102752
• 负责人: A/Prof Anastasios Polyzos
• 金额: $ 40.79万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2023
• 资助国家: 澳大利亚
• 起止时间: 2023-01-01 至 2025-12-31
• 项目状态: 未结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP230102752
• 关键词: Photoinduced; Palladium; Catalysis; Next; Generation

This project aims to discover new methods for the conversion of carbon-hydrogen bonds in organic molecules as a general strategy in chemical synthesis. A key conceptual advance in this project is the unification of transition metal catalysis and visible light as a powerful tool to activate these traditionally unreactive, yet abundant chemical bonds in alkanes. With application in fields that range from fine chemical production to drug discovery, the overarching aim of this research is to establish new carbon-hydrogen bond activation reactions and to demonstrate that this strategy can be translated to the invention of new pharmaceuticals, agrochemicals and advanced synthetic materials that will have societal impact.

该项目旨在发现有机分子中碳-氢键转化的新方法，作为化学合成中的一般策略。该项目的一个关键概念进展是过渡金属催化和可见光的统一，作为激活烷烃中这些传统上无活性但丰富的化学键的有力工具。这项研究的主要目的是建立新的碳氢键活化反应，并证明这一战略可以转化为具有社会影响的新药物、农用化学品和先进合成材料的发明，应用于从精细化工生产到药物开发的各个领域。