Next Generation Photocatalysis for Chemical Synthesis and Manufacture

该项目旨在发现有机分子中能量需求键的激活新方法，作为化学合成的一般策略。在这个项目中，一个关键的概念上的进步是多光子光氧化还原催化的发展，这是一个强大的工具，可以激活传统上不活跃的，但在有机分子中丰富的化学键，包括烷烃和烯烃原料中的碳氢键。从精细化学品生产到药物发现等领域的应用，本研究的总体目标是建立新的键激活反应，并证明转化为将产生社会影响的新药、农用化学品和先进化学制造工艺的发明。

This project aims to discover new methods for the activation of energy demanding bonds in organic molecules as a general strategy in chemical synthesis. A key conceptual advance in this project is the development of multiphoton photoredox catalysis as a powerful tool to activate traditionally unreactive, yet abundant chemical bonds in organic molecules including C-H bonds in alkane and olefin feedstocks. With application in fields that range from fine chemical production to drug discovery, the overarching aim of this research is to establish new bond activation reactions and to demonstrate translations to the invention of new pharmaceuticals, agrochemicals and advanced chemical manufacturing processes that will have societal impact.