Next Generation Photocatalysis for Chemical Synthesis and Manufacture

这个项目的目的是发现激活有机分子中需要能量的键的新方法，作为化学合成的一般策略。该项目的一个关键概念进展是多光子光氧化还原催化的发展，它是一种强大的工具，可以激活有机分子中传统上不具反应性的但丰富的化学键，包括烷烃和烯烃原料中的C-H键。这项研究的主要目的是建立新的键活化反应，并展示对将产生社会影响的新药物、农用化学品和先进化学制造工艺的发明的转化，应用于从精细化工生产到药物发现的各个领域。

This project aims to discover new methods for the activation of energy demanding bonds in organic molecules as a general strategy in chemical synthesis. A key conceptual advance in this project is the development of multiphoton photoredox catalysis as a powerful tool to activate traditionally unreactive, yet abundant chemical bonds in organic molecules including C-H bonds in alkane and olefin feedstocks. With application in fields that range from fine chemical production to drug discovery, the overarching aim of this research is to establish new bond activation reactions and to demonstrate translations to the invention of new pharmaceuticals, agrochemicals and advanced chemical manufacturing processes that will have societal impact.