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Obesity and nutritional programming of the paternal sperm epigenome: effects on offspring development and health

Obesity and nutritional programming of the paternal sperm epigenome: effects on offspring development and health
父亲精子表观基因组的肥胖和​​营养规划:对后代发育和健康的影响
批准号:
313973
负责人:
Kimmins Sarah
金额:
$7.29万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2014
资助国家:
加拿大
项目状态:
已结题
起止时间:
2014-05-01 至 2015-05-01

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中文摘要
翻译
新生儿死亡的最大原因是出生缺陷,发生率为1/33。在50%的病例中,原因不明。出生缺陷的预防是针对母亲的,但父亲贡献了50%的遗传信息。 这个莫
英文摘要
The greatest cause of neonatal death is birth defects, which occur at a rate of 1/33 births. In 50% of cases the cause is unknown. Prevention of birth defects is directed at the mother, yet the father contributes 50% of the heritable information. This mo
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会议论文
Identifying molecular mechanisms underlying the regulatory role of sperm chromatin in embryo development and adult disease
  • 批准号:
    451944
  • 项目类别:
    Operating Grants
  • 资助金额:
    $67.15万
  • 财政年份:
    2021
  • 负责人:
    Kimmins Sarah
  • 依托单位:
Identification of functional epigenomic regions in sperm that are environmentally responsive and associate with fertility and embryo development
  • 批准号:
    451908
  • 项目类别:
    Operating Grants
  • 资助金额:
    $64.09万
  • 财政年份:
    2021
  • 负责人:
    Kimmins Sarah
  • 依托单位:
Canada Research Chair - Tier 1
  • 批准号:
    454009
  • 项目类别:
  • 资助金额:
    $101.99万
  • 财政年份:
    2021
  • 负责人:
    Kimmins Sarah
  • 依托单位:
Generational and sex-specific effects of paternal environmental exposures on offspring development health
  • 批准号:
    338527
  • 项目类别:
    Operating Grants
  • 资助金额:
    $109.28万
  • 财政年份:
    2015
  • 负责人:
    Kimmins Sarah
  • 依托单位:
海外基金