Isolation and Utilization of Bacteria for Co-Culture Bio- degradation of Polychlorinated Biphenyls

共培养生物降解多氯联苯细菌的分离与利用

• 批准号: 8802363
• 负责人: Dennis Focht
• 金额: $ 1.72万
• 依托单位: University of California-Riverside
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1988
• 资助国家: 美国
• 起止时间: 1988-06-01 至 1990-11-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=8802363&HistoricalAwards=false
• 关键词: Isolation; Utilization; Bacteria; Co; Culture

This award will support Professor Dennis D. Focht of the University of California in collaboration with Dr. Blanca Hernandez of the University of Panama, for the purpose of isolating bacteria that metabolize biphenyl compounds. Bacteria will be isolated from the untreated industrial and domestic waste canals of Panama City, Panama, where a great diversity of such organisms has been found. Isolation of a wide variety of biphenyl-metabolizing bacteria may lead to efficient combinations capable of degrading even polychlorinated biphenyls (PCBs) in the environment. Polychlorinated biphenyls are widespread contaminants in the global ecosystem and represent a potential hazard in dump sites in industrialized countries. Biodegradation represents an alternative strategy to incineration of PCB-contaminated soils. To date, bacteria using PCBs as growth substrates have not been isolated and probably do not exist in nature. Nevertheless, considerable progress has been made in selectively isolating bacteria that use biphenyl as a growth substrate. These bacteria partially metabolize PCBs by isolating part of the enzyme system while growing on biphenyl, the non-chlorinated analog. By combining Professor Focht's expertise with biodegradation, with access to a rich and varied sample of microorganisms, this project enhances the capability of research scientists in a developing country and is of mutual benefit, thus fulfilling an important criterion of the Science in Developing Countries Program.

该奖项将支持丹尼斯D教授。福赫特 加州大学与布兰卡博士合作 巴拿马大学的埃尔南德斯，为了 分离代谢联苯化合物的细菌。细菌 将与未经处理的工业和家庭 巴拿马巴拿马城的废弃运河， 已经发现了这样的微生物。分离出各种各样的 联苯代谢细菌可能导致有效的 甚至能够降解多氯联苯的组合物 环境中的多氯联苯。 多氯联苯是一种广泛存在于环境中的污染物， 对全球生态系统构成潜在危害， 在工业化国家。 生物降解是一种 焚烧多氯联苯污染土壤的替代战略。 到目前为止，使用多氯联苯作为生长基质的细菌还没有被发现。 孤立的，可能不存在于自然界中。 然而，尽管如此， 在有选择地隔离 使用联苯作为生长基质的细菌。 这些 细菌通过分离部分多氯联苯， 酶系统，而生长在联苯，非氯化 analog. 通过将福赫特教授的专业知识与 生物降解，获得丰富多样的样品， 微生物，该项目提高了研究能力 科学家在发展中国家，是互利的， 从而满足了科学的一个重要标准， 发展中国家方案。