Neural circuit control of effort under stress

压力下努力的神经回路控制

• 批准号: DP230102566
• 负责人: Dr Susannah Tye
• 金额: $ 45.79万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2023
• 资助国家: 澳大利亚
• 起止时间: 2023-03-13 至 2026-03-12
• 项目状态: 未结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP230102566
• 关键词: Neural; circuit; control; effort; under

This Project aims to investigate how the ‘decision’ to persist in exerting effort to obtain a reward is encoded in the the brain and affected by stress. This work will generate new knowledge on the neural mechanisms through which stress modifies neural activity to control decision making processes underpinning adaptive behaviours essential for survival. The expected outcomes of this work include enhanced capacity at the interface of behavioural and computational neuroscience, that will in turn provide significant benefits through greater insight into brain functions essential for survival, with long ranging implications for performance optimisation and brain-inspired computing.

本项目旨在研究如何“决定”坚持努力获得奖励是在大脑中编码和压力的影响。这项工作将产生关于神经机制的新知识，通过这种机制，压力会改变神经活动，以控制决策过程，支持生存所必需的适应行为。这项工作的预期成果包括增强行为和计算神经科学接口的能力，这反过来将通过更深入地了解生存所必需的大脑功能提供显着的好处，对性能优化和脑启发计算具有长期影响。