Research Facilities for the Center for Gene Research and Biotechnology

在过去的几年中，自动化蛋白质测序和肽合成设备的使用已经成为生物科学许多领域研究进展的关键。蛋白质氨基酸序列的测定通常是对编码蛋白质的基因或DNA进行分离和随后的序列分析所必需的第一步。肽的合成通常是蛋白质和基因调控的功能和结构方面的现代分析的重要步骤。该奖项提供的资金将用于购买用于纯化蛋白质和合成肽的仪器，以及蛋白质的自动测序。该设备将与现有的和其他新的仪器一起安置在中央服务实验室，并将致力于为俄勒冈州立大学校园的大约50名研究人员提供服务。提案中讨论项目的研究人员活跃于动物、植物和细菌病毒学、神经生物学、细胞生物化学、酶学或生物物理学。

The use of equipment for automated protein sequencing and peptide synthesis has, in the last few years, become crucial to the progress of research in many areas of biological science. Determination of the amino acid sequence of a protein is often a required initial step in the isolation and subsequent sequence analysis of the gene, or DNA, that encodes the protein. Synthesis of peptides is often an important step for modern analysis of functional and structural aspects of proteins and of the regulation of genes. The funds provided by this award will be used to purchase instruments that perform purification of proteins and synthetic peptides, and the automated sequencing of proteins. The equipment will be housed with existing and other new instrumentation in the Central Service Laboratory, and will be devoted to providing service to approximately 50 researchers on the Oregon State campus. Researchers whose projects are discussed in the proposal are active in animal, plant and bacterial virology, neurobiology, cellular biochemistry, enzymology, or biophysics.