Research Facilities for the Center for Gene Research and Biotechnology

在过去的几年里，使用自动蛋白质测序和多肽合成的设备已经成为许多生物科学领域研究进展的关键。确定蛋白质的氨基酸序列通常是分离和随后对编码蛋白质的基因或DNA进行序列分析的必要的初始步骤。多肽的合成通常是现代蛋白质功能和结构分析以及基因调控的重要步骤。这项奖励提供的资金将用于购买进行蛋白质和合成肽纯化以及蛋白质自动测序的仪器。这些设备将与现有的和其他新的仪器一起安置在中央服务实验室，并将致力于为俄勒冈州立大学校园内的大约50名研究人员提供服务。提案中讨论的项目的研究人员活跃在动物、植物和细菌病毒学、神经生物学、细胞生物化学、酶学或生物物理学领域。

The use of equipment for automated protein sequencing and peptide synthesis has, in the last few years, become crucial to the progress of research in many areas of biological science. Determination of the amino acid sequence of a protein is often a required initial step in the isolation and subsequent sequence analysis of the gene, or DNA, that encodes the protein. Synthesis of peptides is often an important step for modern analysis of functional and structural aspects of proteins and of the regulation of genes. The funds provided by this award will be used to purchase instruments that perform purification of proteins and synthetic peptides, and the automated sequencing of proteins. The equipment will be housed with existing and other new instrumentation in the Central Service Laboratory, and will be devoted to providing service to approximately 50 researchers on the Oregon State campus. Researchers whose projects are discussed in the proposal are active in animal, plant and bacterial virology, neurobiology, cellular biochemistry, enzymology, or biophysics.