NSF Facilities Center

在过去几年中，对蛋白质和DNA进行自动测序的设备的使用对生物科学几乎所有领域的研究进展都至关重要。蛋白质氨基酸序列的测定通常是对编码蛋白质的基因或DNA进行分离和随后的序列分析所必需的第一步。物种间序列变异的研究为现代分析系统和进化关系提供了必要的信息，并经常使人们对蛋白质、rna和基因的功能和结构方面有深入的了解。该奖项提供的资金将用于购买执行蛋白质和DNA自动测序的仪器。这些设备将与现有和其他新仪器一起安置在一个设施中，所有这些设备都将致力于为佛罗里达州立大学校园的所有研究人员提供服务。提案中所讨论项目的研究人员活跃于进化与系统学、细胞生物学、遗传学、免疫学、酶学、内分泌学和微生物生态学。

The use of equipment for the automated sequencing of proteins and DNA has, in the last few years, become crucial to the progress of research in virtually all areas of biological science. Determination of the amino acid sequence of a protein is often a required initial step in the isolation and subsequent sequence analysis of the gene, or DNA, that encodes the protein. Studies of sequence variation between species provide essential information for modern analysis of systematic and evolutionary relationships, and often give insight into functional and structural aspects of proteins, of RNAs and of genes. The funds provided by this award will be used to purchase instruments that perform automated sequencing of proteins and DNA. The equipment will be housed in a facility together with existing and other new instrumentation, all of which will be devoted to providing service to all researchers on the Florida State campus. Researchers whose projects are discussed in the proposal are active in evolution and systematics, cell biology, genetics, immunology, enzymology, endocrinology, and microbial ecology.