NSF Facilities Center

美国国家科学基金会设施中心

• 批准号: 8804194
• 负责人: Lawrence Abele
• 金额: $ 20万
• 依托单位: Florida State University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1989
• 资助国家: 美国
• 起止时间: 1989-03-01 至 1992-02-29
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=8804194&HistoricalAwards=false
• 关键词: NSF; Facilities; Center

The use of equipment for the automated sequencing of proteins and DNA has, in the last few years, become crucial to the progress of research in virtually all areas of biological science. Determination of the amino acid sequence of a protein is often a required initial step in the isolation and subsequent sequence analysis of the gene, or DNA, that encodes the protein. Studies of sequence variation between species provide essential information for modern analysis of systematic and evolutionary relationships, and often give insight into functional and structural aspects of proteins, of RNAs and of genes. The funds provided by this award will be used to purchase instruments that perform automated sequencing of proteins and DNA. The equipment will be housed in a facility together with existing and other new instrumentation, all of which will be devoted to providing service to all researchers on the Florida State campus. Researchers whose projects are discussed in the proposal are active in evolution and systematics, cell biology, genetics, immunology, enzymology, endocrinology, and microbial ecology.

蛋白质自动测序设备的使用， 在过去的几年里，DNA已经成为人类进化的关键。 几乎所有生物科学领域的研究。 测定 蛋白质氨基酸序列的起始位置通常是 基因的分离和随后的序列分析步骤，或 编码蛋白质的DNA 序列变异的研究 物种提供了重要的信息，为现代分析的系统 和进化的关系，并经常提供洞察功能 以及蛋白质、RNA和基因的结构方面。 本次奖励提供的资金将用于购买 对蛋白质和DNA进行自动测序的仪器。 的 设备将与现有设备和其他设备一起存放在一个设施中 新的仪器，所有这些都将致力于提供服务， 致佛罗里达州立大学的所有研究人员 研究人员， 提案中讨论的项目正在积极发展， 系统学，细胞生物学，遗传学，免疫学，酶学， 内分泌学和微生物生态学。