ApoB-lipoproteins, adipose tissue NLRP3 inflammasome and insulin resistance

ApoB 脂蛋白、脂肪组织 NLRP3 炎性体和胰岛素抵抗

• 批准号: 247148
• 负责人: Faraj May
• 金额: $ 7.29万
• 依托单位: Institut de recherches cliniques de Montral
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2011
• 资助国家: 加拿大
• 起止时间: 2011-09-01 至 2012-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=247148&lang=en
• 关键词: 12 Weeks Omega-3 Fatty Acids-Rich Diet; In Vivo And And Ex Vivo Human And Mice Models; Innate Immunity And Nlrp3 Inflammasome; Insulin Sensitivity And Secretion; Lipids And Apob-Lipoproteins; Overweight And Obese Subjects; Postprandial Fat Clearance; Stab

In this project we will investigate the role of the particles that carry lipids in the blood in the promotion of immunity pathways leading to fat tissue dysfunction and other risks for type 2 diabetes in humans. We will also investigate the role of omega-

在这个项目中，我们将研究血液中携带脂质的颗粒在促进导致脂肪组织功能障碍和人类 2 型糖尿病其他风险的免疫途径中的作用。我们还将研究欧米伽的作用