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Targeting hyperapoB vs normoapoB to reduce the risk of type 2 diabetes in obese subjects; mechanism of action

Targeting hyperapoB vs normoapoB to reduce the risk of type 2 diabetes in obese subjects; mechanism of action
相对于normoapoB,靶向hyperapoB可降低肥胖受试者患2型糖尿病的风险;
批准号:
172911
负责人:
Faraj May
金额:
$29.5万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2008
资助国家:
加拿大
项目状态:
已结题
起止时间:
2008-09-01 至 2011-09-01

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中文摘要
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英文摘要
Background: Type 2 diabetes results in the yearly death of ~ 40,000 Canadians. Some obese subjects have higher risk to develop diabetes and my research will examine why. The risk for type 2 diabetes in obese subjects increases when the body is resistance
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White adipose tissue LDL receptors and omega-3 as modulators of the risk for type 2 diabetes
The inflammasome and dysfunctional adipose tissue: why should apoB-lipoproteins be targeted in humans
ApoB-lipoproteins, adipose tissue NLRP3 inflammasome and insulin resistance