The inflammasome and dysfunctional adipose tissue: why should apoB-lipoproteins be targeted in humans

炎症小体和功能失调的脂肪组织：为什么应将 apoB 脂蛋白作为人类的靶标

• 批准号: 253614
• 负责人: Faraj May
• 金额: $ 52.46万
• 依托单位: Institut de recherches cliniques de Montral
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2012
• 资助国家: 加拿大
• 起止时间: 2012-03-01 至 2017-03-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=253614&lang=en
• 关键词: 16 Wks Omega-3 Fatty Acids Supplementation; Clinical Study In Obese Subjects; In Vivo And And Ex Vivo Models; Innate Immunity And Nlrp3 Inflammasome; Insulin Sensitivity And Secretion; Lipoprotein Metabolism; Postprandial Dietary Fat Clearance; Stable And

While obesity increases the risk for cardiometabolic diseases like cardiovascular disease and diabetes, not all obese are at equal risk for these diseases. Unravelling the mechanisms that predict and promote diabetes is vital to identify and treat the hig

虽然肥胖会增加患心血管疾病和糖尿病等心脏代谢疾病的风险，但并非所有肥胖者患这些疾病的风险都相同。揭示预测和促进糖尿病的机制对于识别和治疗高血糖至关重要。