Functional and Molecular Characterization of the Novel Chondrocyte-Specific Gene Smpec

新型软骨细胞特异性基因 Smpec 的功能和分子表征

• 批准号: 250214
• 负责人: Moffatt Pierre
• 金额: $ 7.29万
• 依托单位: Shriners Hospital for Children (Montral)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2011
• 资助国家: 加拿大
• 起止时间: 2011-09-01 至 2012-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=250214&lang=en
• 关键词: Chondrocyte; Growth Plate; Membrane Protein; Molecular And Cellular Biology; Proteoglycan; Skeletal Biology; Transgenesis And Knockout

We have discovered a novel gene called Smpec that is expressed only in the skeleton. The SMPEC protein is present at the surface of chondrocytes. Chondrocytes are cells of the skeleton that are important for the development and growth of all long bones.

我们发现了一种名为Smpec的新基因，它只在骨骼中表达。SMPEC蛋白存在于软骨细胞的表面。软骨细胞是骨骼的细胞，对所有长骨的发育和生长都很重要。