Mechanical Power Output of Muscle

横纹肌的机械功率输出将通过测量肌肉张力来确定，因为肌肉受到周期性长度变化和在长度周期的选定阶段发生的刺激。在一个循环中，肌肉张力与长度的关系图形成了一个循环，其面积是该循环中肌肉所做功或作用于肌肉的功。该项目的目标是：1)将昆虫翅膀肌肉的机械动力测量与同时测量的耗氧量相结合，以测量肌肉将代谢转化为机械动力的效率，并确定最大功率输出的操作条件是否也是最大效率的操作条件。2)将功率测量扩展到昆虫翅膀肌肉以外的肌肉，以确定不同来源的肌肉在机械功率输出能力方面的相似或不同程度。3)描述刺激后不同时间缩短和延长肌肉的力-速度曲线，并利用这些信息创建一个模型，该模型将允许估计肌肉在周期性长度变化和相位刺激下的功率输出。4)表征肌肉的释放失活，并确定释放失活在多大程度上影响重复收缩时的功率输出。

The mechanical power output of a striated muscle will be determined by measuring muscle tension as the muscle is subjected to periodic length change and to stimuli which occur at selected phases of the length cycle. The plot of muscle tension against length over a cycle forms a loop whose area is the work done by or on the muscle for that cycle. The goals of this project are: 1) To combine mechanical power measurements from insect wing muscles with simultaneous measurement of oxygen consumption in order to measure the efficiency of the muscle in converting metabolic to mechanical power, and to determine if the operating conditions which maximize power output are also those which maximize efficiency. 2) To extend power measurements to muscles other than insect wing muscles in order to determine how similar or dissimilar are muscles from different sources in their capacity for mechanical power output. 3) To characterize force- velocity curves for both shortening and lengthening muscles at different times after stimulation, and to use this information to create a model which will allow estimation of the power output from a muscle subjected to periodic length change and phasic stimulation. 4) To characterize release inactivation in muscle, and to determine the extent to which release inactivation affects power output during repetitive contraction.