High specificity nanosensors for glycobiology

该项目旨在开发用于识别和表征碳水化合物的高特异性糖传感器。这些糖传感器有望产生关于碳水化合物立体化学结构的详细信息，以及这种结构如何控制蛋白质与碳水化合物的结合以及生化过程中基本的其他相互作用。这项创新的纳米技术旨在提供一种新的能力来理解细胞识别和抗原结合机制。预期的成果是糖生物学和碳水化合物结构-功能关系研究的新工具，凭借针对生物医学科学和许多利用碳水化合物的行业的精辟分析技术，加强澳大利亚在纳米传感器领域的全球声誉。

This project aims to develop high specificity glycosensors for identifying and characterising carbohydrates. These glycosensors are expected to generate detailed information on carbohydrate stereochemical structure and how this controls protein-carbohydrate binding and other interactions fundamental to biochemical processes. This innovative nanotechnology aims to deliver a new capability for understanding cellular recognition and antigen binding mechanisms. The expected outcomes are new tools for glycobiology and research into carbohydrate structure-function relationships, strengthening Australia’s global reputation in nanosensors with an incisive analytical technology for biomedical sciences and the many industries utilising carbohydrates.