The cellular stress response regulator ATF3 is a novel mediator of platin induced tumour cell cytotoxicity and resistance

细胞应激反应调节剂 ATF3 是铂诱导肿瘤细胞细胞毒性和耐药性的新型介质

• 批准号: 260855
• 负责人: Dimitroulakos Jim
• 金额: $ 7.29万
• 依托单位: Ottawa Hospital Research Institute
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2012
• 资助国家: 加拿大
• 起止时间: 2012-03-01 至 2013-03-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=260855&lang=en
• 关键词: Cell Signaling; Experimental Therapeutics; Metabolic Stress Pathways; Platins

There is an enormous urgency for new and innovative treatments for patients with lung cancer. In this common and deadly disease, chemotherapy has provided only marginal benefits for patients with metastatic disease with platin based agents showing the gre

对于肺癌患者来说，新的和创新的治疗方法非常紧迫。在这种常见而致命的疾病中，化疗仅为转移性疾病患者提供了边际效益，