Targeting the mevalonate pathway in novel combination based therapeutic approaches
Targeting the mevalonate pathway in novel combination based therapeutic approaches
批准号:
291598
负责人:
Dimitroulakos Jim
金额:
$25.49万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2013
资助国家:
加拿大
项目状态:
已结题
起止时间:
2013-09-01 至 2016-09-01
中文摘要
我们发现了他汀类药物家族的一种新特性,这些药物被广泛用于通过靶向甲羟戊酸途径来治疗高血清胆固醇水平。该途径的最终产物,包括胆固醇,在控制
英文摘要
We identified a new property of the statin family of drugs that are used extensively to treat high serum cholesterol levels through targeting of the mevalonate pathway. This pathway's end products including cholesterol play important roles in controlling
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会议论文
The cellular stress response regulator ATF3 is a novel mediator of platin induced tumour cell cytotoxicity and resistance
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批准号:260855
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项目类别:Operating Grants
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资助金额:$7.29万
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财政年份:2012
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负责人:Dimitroulakos Jim
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依托单位:
海外基金