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Discovery and Development of Small Molecule Toxin Antagonists to Treat C. difficile-Associated Disease

Discovery and Development of Small Molecule Toxin Antagonists to Treat C. difficile-Associated Disease
治疗艰难梭菌相关疾病的小分子毒素拮抗剂的发现和开发
批准号：
266523
负责人：
Melnyk Roman
金额：
$36.41万
依托单位：
Hospital for Sick Children (Toronto)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2012
资助国家：
加拿大
项目状态：
已结题
起止时间：
2012-09-01 至 2017-09-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=266523&lang=en
关键词：
Bacterial Toxins Clostridium Difficile Drug Discovery High Throughput Screening In Vivo Efficacy Infectious Diseases Microbiology Pathogenesis Phenotypic Screening Virulence

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中文摘要
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英文摘要
In the past decade, there have been several outbreaks of Clostridium difficile ("C.diff") in hospitals across Canada and around the world due to the emergence of more infectious strains of this microbe. These "superbug" strains are troubling because they
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    480581
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    2016
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