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Elucidating a new role for bile acids in protecting against C. difficile toxin pathogenesis: Implications for therapy

Elucidating a new role for bile acids in protecting against C. difficile toxin pathogenesis: Implications for therapy
阐明胆汁酸在抵御艰难梭菌毒素发病机制中的新作用:对治疗的意义
批准号:
371788
负责人:
Melnyk Roman
金额:
$48.9万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2017
资助国家:
加拿大
项目状态:
已结题
起止时间:
2017-09-01 至 2022-09-01

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中文摘要
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英文摘要
Clostridium difficile (C.diff) is the leading cause of hospital-acquired diarrhea in the developed world. This opportunistic bacterium is a major problem in hospitals for three main reasons. The first is that C.diff is able to form highly resilient spores
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13th International Conference on Molecular Biology and Pathogenesis of Clostridia (Clostpath)
  • 批准号:
    480581
  • 项目类别:
    Miscellaneous Programs
  • 资助金额:
    $1.46万
  • 财政年份:
    2023
  • 负责人:
    Melnyk Roman
  • 依托单位:
Development of a tumour-targeted RAS-specific protease for pancreatic cancer therapy
  • 批准号:
    434733
  • 项目类别:
    Operating Grants
  • 资助金额:
    $64.09万
  • 财政年份:
    2020
  • 负责人:
    Melnyk Roman
  • 依托单位:
Development of a Novel Platform to Treat Neuropathic Lysosomal Storage Diseases
  • 批准号:
    345890
  • 项目类别:
    Operating Grants
  • 资助金额:
    $49.01万
  • 财政年份:
    2016
  • 负责人:
    Melnyk Roman
  • 依托单位:
Discovery and Development of Small Molecule Toxin Antagonists to Treat C. difficile-Associated Disease
  • 批准号:
    266523
  • 项目类别:
    Operating Grants
  • 资助金额:
    $36.41万
  • 财政年份:
    2012
  • 负责人:
    Melnyk Roman
  • 依托单位:
海外基金