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Cardioprotection through a reduction in cardiac CapZ

Cardioprotection through a reduction in cardiac CapZ
通过减少心脏 CapZ 来保护心脏
批准号:
267386
负责人:
Pyle Glen W
金额:
$19.14万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2012
资助国家:
加拿大
项目状态:
已结题
起止时间:
2012-09-01 至 2015-09-01

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中文摘要
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英文摘要
In heart failure, cardiac muscle contraction is negatively altered by a family of molecules called "Protein Kinase C" (PKC). We found that reducing CapZ protein blocks PKC-dependent inhibition of contraction. We hypothesized that reducing CapZ protects he
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Getting to the Heart of Domestic Abuse: Identifying the molecular mechanisms of heart disease in association with physical and psychological stress
  • 批准号:
    486978
  • 项目类别:
    Operating Grants
  • 资助金额:
    $10.93万
  • 财政年份:
    2023
  • 负责人:
    Pyle Glen W
  • 依托单位:
Cardioprotection through manipulation of CapZ
  • 批准号:
    420302
  • 项目类别:
    Operating Grants
  • 资助金额:
    $45.2万
  • 财政年份:
    2020
  • 负责人:
    Pyle Glen W
  • 依托单位:
Sex and the Ageing Heart: The molecular basis for the functional decline and development of a novel therapeutic target
  • 批准号:
    339909
  • 项目类别:
    Operating Grants
  • 资助金额:
    $10.88万
  • 财政年份:
    2015
  • 负责人:
    Pyle Glen W
  • 依托单位:
海外基金