Cardioprotection through a reduction in cardiac CapZ
Cardioprotection through a reduction in cardiac CapZ
批准号:
267386
负责人:
Pyle Glen W
金额:
$19.14万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2012
资助国家:
加拿大
项目状态:
已结题
起止时间:
2012-09-01 至 2015-09-01
中文摘要
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英文摘要
In heart failure, cardiac muscle contraction is negatively altered by a family of molecules called "Protein Kinase C" (PKC). We found that reducing CapZ protein blocks PKC-dependent inhibition of contraction. We hypothesized that reducing CapZ protects he
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依托单位:
海外基金