Purchase of a Routine Fourier Transform NMR Instrument

购买常规傅里叶变换核磁共振仪

• 批准号: 8820644
• 负责人: G. Edwin Wilson
• 金额: $ 16.24万
• 依托单位: University of Akron
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1989
• 资助国家: 美国
• 起止时间: 1989-03-01 至 1990-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=8820644&HistoricalAwards=false
• 关键词: Purchase; Routine; Fourier; Transform; NMR

Nuclear Magnetic Resonance (NMR) spectroscopy is the most powerful tool available to the chemist for the elucidation of the structure of molecules. It is used to identify unknown substances, characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectroscopy is essential to chemists and biologists who are carrying out frontier research. The Department of Chemistry at the University of Akron will use this award from the Chemistry Shared Instrumentation Program and the Instrumentation and Instrument Development Program to help acquire a high-field NMR spectrometer. The areas of research that will be enhanced by the acquisition include: 1) Mechanisms of enzymatic reactions 2) Transition metal catalysis of polymerization reactions 3) Development and study of the chemistry of iodinane reagents 4) New 2D-NMR techniques for studying weak intermolecular interactions 5) Enzymatic catalysts for carrying out synthetic transformations 6) Solution structures and conformations of enzyme active sites.

核磁共振波谱是化学家用来阐明分子结构的最有力的工具。它被用来识别未知物质，表征分子内原子的特定排列，并研究溶液中分子之间相互作用的动力学。对于从事前沿研究的化学家和生物学家来说，接触最先进的核磁共振波谱是必不可少的。阿克伦大学化学系将利用化学共享仪器计划以及仪器和仪器开发计划授予的这一奖项，帮助获得高场核磁共振光谱仪。收购将加强的研究领域包括：1)酶反应机理2)过渡金属催化聚合反应3)碘烷试剂化学的发展和研究4)研究弱分子间相互作用的2D-核磁共振新技术5)用于合成转化的酶催化剂6)酶活性中心的溶液结构和构象。