Molecular structure of the Staphylococcal antibiotic resistance protein AAC(6')-Ie/APH(2'')-Ia: structural analysis as a starting point in combating clinical resistance

葡萄球菌抗生素耐药性蛋白 AAC(6)-Ie/APH(2)-Ia 的分子结构：结构分析作为对抗临床耐药性的起点

• 批准号: 283784
• 负责人: Caldwell Shane J
• 金额: $ 7.65万
• 依托单位: McGill University
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2012
• 资助国家: 加拿大
• 起止时间: 2012-10-01 至 2015-10-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=283784&lang=en
• 关键词: Antibiotic Resistance; Antimicrobial Development; Biochemistry; Drug Design; Enzymology; Protein Crystallization; Protein Purification; Structural Biology; X-Ray Crystallography; X-Ray Scattering (Saxs)

Antibiotic resistance is one of the most serious problems affecting the future of medicine, in Canada and worldwide. Resistance exists for every antibiotic used in the clinic, and multiple drug-resistant bacteria such as methicillin-resistant Staphylococc

在加拿大和世界范围内，抗生素耐药性是影响未来医学的最严重问题之一。临床上使用的每一种抗生素都存在耐药性，而且多种耐药细菌，如耐甲氧西林的葡萄球菌