Synthetic biology-enabled identification of novel antibiotic resistance mechanisms using de novo proteins to screen for emergent activities
Synthetic biology-enabled identification of novel antibiotic resistance mechanisms using de novo proteins to screen for emergent activities
批准号:
362226
负责人:
Caldwell Shane J
金额:
$10.93万
依托单位国家:
加拿大
项目类别:
Fellowship Programs
财政年份:
2016
资助国家:
加拿大
项目状态:
已结题
起止时间:
2016-11-01 至 2019-11-01
中文摘要
抗生素耐药性仍然是现代医学面临的最紧迫的危机之一。我们使用抗生素作为对抗细菌的武器,而细菌则想方设法转移我们的攻击。
现有的耐药性形式使目前的抗生素无法发挥作用,
英文摘要
Antibiotic resistance remains one of the most pressing crises facing modern medicine. We use antibiotics as weapons against bacteria, while bacteria find ways of deflecting our attack.
Existing forms of resistance make current antibiotics nonfunctional, a
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会议论文
Molecular structure of the Staphylococcal antibiotic resistance protein AAC(6')-Ie/APH(2'')-Ia: structural analysis as a starting point in combating clinical resistance
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批准号:283784
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项目类别:Studentship Programs
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资助金额:$7.65万
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财政年份:2012
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负责人:Caldwell Shane J
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依托单位:
海外基金