Acquisition of a Multinuclear High-Field Fourier Transform Nuclear Magnetic Resonance Spectrometer

核磁共振波谱是化学家用来阐明分子结构的最强大的工具。它被用来识别未知物质，表征分子内原子的特定排列，并研究溶液中分子之间相互作用的动力学。对于从事前沿研究的化学家和生物学家来说，接触最先进的核磁共振波谱是必不可少的。波特兰州立大学化学系(以本科生为主)将利用化学共享仪器计划以及仪器和仪器开发计划授予的这一奖项，帮助获得高场核磁共振光谱仪。此次收购将加强以下化学和生物学领域的研究活动：1)与人工膜相关的化合物光合作用2)含氟低分子化合物和聚合物3)高价铬氧化剂4)大气反应产物5)缺电子杂环pi体系6)光系统I中氟连接的铁硫簇合物7)小铁硫蛋白的结构8)蛋白质变性热力学9)用NOE研究钙结合蛋白的结构。

Nuclear Magnetic Resonance (NMR) spectroscopy is the most powrful tool available to the chemist for the elucidation of the structure of molecules. It is used to identify unknown substances, characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectroscopy is essential to chemists and biologists who are carrying out frontier research. The Department of Chemistry at Portland State University (a Predominantly Undergraduate Institution) will use this award given by the Chemistry Shared Instrumentation Program and the Instrumentation and Instrument Development Program to help acquire a high-field NMR spectrometer. The acquisition will enhance research actvity in the following areas of chemistry and biology: 1) Compounds relevant to membranes for artificial photosynthesis 2) Fluorine-containing low molecular weight compounds and polymers 3) High valent chromium oxidants 4) Atmospheric reaction products 5) Electron deficient heterocyclic pi-systems 6) Fluorine-ligated iron-sulfur clusters in photosystem I 7) Structure of a small iron-sulfur protein 8) Protein thermodynamics probed by denaturation 9) Structure of calcium-binding proteins using NOE.